Eventually, as you learn more and more about pre-flight checks and what the various controls do, you’ll be faced with your first real challenge in Microsoft Flight Simulator: Taking off. The good news is the procedure is the same for all planes so it can be applied across the board upon learning it.
The first step is to switch off the safety brakes (Ctrl + Num Delete). You can also manually click on the switch in the instrumental panel with the mouse. Approach the runway and press F1 to start the throttle. Ensure that the plane’s nose is facing up by pressing Numpad 1 on the keyboard. Keep the plane in this position upon lift-off and avoid making any other sudden movements. Once you’re in the air, it’s safe to release the plane’s nose and fly as per usual.
To see the entire take-off process in action, check out the video guide below.